EFFICACY OF SOFOSBUVIR AS TREATMENT FOR YELLOW FEVER: PROTOCOL FOR A RANDOMISED CONTROLLED TRIAL IN BRAZIL (SOFFA STUDY)

Efficacy of sofosbuvir as treatment for yellow fever: protocol for a randomised controlled trial in Brazil (SOFFA study)

Introduction An ongoing outbreak of yellow fever (YF) has been reported in Brazil with 1261 confirmed cases and 409 deaths since July 2017.To date, there is no specific treatment available for YF.Recently published papers describing in vitro Steel Wool and animal models suggest a potential effect of antiviral drugs (approved for the treatment of he

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Reduced Numerical Approximation of Reduced Fluid-Structure Interaction Problems With Applications in Hemodynamics

This paper deals with fast simulations of the hemodynamics in large arteries by considering a reduced model of the associated fluid-structure interaction problem, which in turn allows an additional reduction in terms of the numerical discretisation.The resulting method is both accurate and computationally cheap.This goal is Hoodie achieved by means

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Construction of an LNG copyright Port State Control Inspection Knowledge Graph by a Dynamic Knowledge Distillation Method

The Port State Control (PSC) inspection of liquefied natural gas (LNG) carriers is crucial in maritime transportation.PSC inspection requires rapid and accurate identification of defects with limited resources, necessitating professional knowledge and efficient technical methods.Knowledge distillation, as a model lightweighting approach in the fiel

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